Natural GLP-1 enhancement through diet and lifestyle remains valuable even when medication is prescribed, as these approaches work synergistically to optimise metabolic health
It is also often used for skin treatment, such as skin whitening
Other studies have shown that laboratory tests for vitamin B12 are mainly used for patients with non-specific symptoms rather than the recommended population 6
Like many medications in this class, the most common side effects are nausea, diarrhea, or stomach upset , especially when starting treatment
Retatrutide's proposed mechanism of action involves GLP-1 receptor activation to slow gastric emptying and promote satiety, GIP receptor activation to support insulin secretion and adipose tissue regulation, and glucagon receptor agonism, which in trial settings has been associated with increased energy expenditure and lipolysis